| Number of extracts |
2,816 |
| Plate Numbers |
2000-2007
(8 Plates) |
| Concentration Information |
Dried extracts resuspended at
~15 mg/ml in DMSO |
| Plate Format |
384-well plate
Plate 2000-2007:
Column 23-24 (empty)
 Click plate image to enlarge
|
This library was plated and added to the collection in Fall 2008. Production of this fungal extract library was funded by an International
Cooperative Biodiversity Groups (ICBG) grant from the NIH to Dr.
Jon Clardy. The library contains partially purified extracts from
diverse organisms that grow in Costa Rica, including lichens, cyanobacteria, sponges, and endophytic fungi (fungi that live in higher plants), and that have been collected and assembled by the National Biodiversity Institute (INBio) in Costa Rica. Crude extracts from the fungi were obtained and further
fractionated to eliminate nuisance compounds, especially those of
high molecular weight or high polarity.
Screening positives that have been confirmed by follow-up experiments on cherry
picked samples can be further fractionated via a collaboration with the lab of
Dr. Jon Clardy (Harvard Medical School). Please contact Caroline Shamu (caroline_shamu@hms.harvard.edu)
to arrange for purification of "hit" compounds from extract samples.
|
