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Instructions
ICCB-Longwood welcomes applications from Harvard Medical School (HMS), Harvard Hospital-affiliated investigators and NERCE affiliates. Applications
must be submitted each time a new screen is proposed. We are currently accepting applications on a rolling basis. If the facility becomes oversubscribed we will institute a waiting list.
Fees are charged for access to RNAi screening at ICCB-Longwood. This fee helps us to recover some of our operating costs. It is revised annually on a schedule based on the Harvard fiscal year (July 1 - June 30), thus updates to the fee structure are generally posted here in the late summer. Please contact Caroline Shamu with questions regarding fee revisions.
(Fees updated August 18, 2008; these fees are being reviewed and new fees will be posted in January 2009) For HMS Quadrangle-based investigators, the RNAi screening fee is $6,030 per screen. For HMS-affiliated investigators whose labs are not located on the HMS quadrangle, the RNAi screening fee is $10,180 ($1,150 of this amount is a charge to cover facilities and administration costs assessed by HMS). For investigators with no HMS affiliation, the fee is $20,929 ($1,150 of this amount is a charge to cover facilities and administration costs assessed by HMS). Interested screeners should contact Caroline Shamu for more details and/or to determine which rate applies to their screen. Please note the RNAi screening fees are in addition to the cost of assay reagents and supplies provided by the screener. The fee will be charged only once screening is underway and not during the development phase of the screen.
The above fees include cherry picks for 2000 individual siRNA duplexes (representing 500 genes) for each screen. Additional cherry picks can be requested at $1 per duplex picked ($4 per gene). Cherry picking will only be carried out for individual duplexes, not for SMARTpool reagents. Cherry picking can only be requested after primary screening of SMARTpool libraries.
For more information about working at ICCB-Longwood to carry
out screening projects, please see our website, http://iccb.med.harvard.edu.
Often, investigators request a Letter of Collaboration for grants
intended to fund a screen. Please understand that we can only write
such a letter if we know that we can accommodate your screen. Therefore,
please try to submit your Application to screen at the ICCB-Longwood well
in advance of grant deadlines, and please warn us if you expect
to need a Letter of Collaboration.
Please send any questions about the ICCB-Longwood Screening Application
or evaluation process to screeniccb_apply"AT"hms.harvard.edu.
If you think you are having problems submitting an Application via this website, please send an explanatory email directly to screeniccb_apply@hms.harvard.edu or to the Director of ICCB-Longwood. Thank you.
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